The Game has run out of memory

I have a tb second F Drive that I use and have used for Sims in the past that's usually where I house it. But, since the memory usage thing popped up I moved it to the c drive for easier accessibility. 

I'm not sure why the monitors are reading as two different technologies. The monitors are identical. The connections are different. One's an hdmi the other is the old school screw in. I can adjust that.  The only programs I've had up is Chrome trying to trouble shoot and skype. Other than that I've had nothing else up while trying to run the game. I cleaned everything trying to figure this out. 

 I tried everything but the gen up. Cause obviously I can't do that right away. I got this