@huzzahitssarahDo you have any CC in your game? If yes - probably some broken CC caused it.
Move the mods folder to the desktop.
Delete localthumbcache.package file in the game folder
Fix the game in Origin.
Origin/Library -right click on TS4 - option "Repair game"
You have to wait until Origin will fix all packs, not only the base game.
Turn on the game to create a new, empty mods folder and to check if a game is working now without mods and CC and this blinking disappeared.
Check if there are new updated versions of the mods and CC you are using.
Then copy from desktop your mods and CC and paste it in the new mods folder. First, paste script mods one by one every time checking if every mod is up to date. Do the same with CC and look for this effect but if you have a lot of this, try the 50/50 method.
I don't work for EA.