Will Lenovo thinkpad w541 or w550s play the sims 4

Of those two, the Quadro K2100M will offer the best performance. This is the default resolution and setting as found in the game files.

    card 0x11fc "NVIDIA Quadro K2100M" $cardLevelHigh $resolutionHigh

Keep in mind that while you may run the game on a Quadro GPU, it may not be officially supported, so there may be unexpected complications.

I would personally advise against getting a Lenovo laptop because of the inclusion of bloatware which installs itself onto the PC even when doing a clean install. (The installers are present in the BIOS.)

http://www.v3.co.uk/v3-uk/news/2422015/lenovo-caught-installing-bloatware-again-with-windows-bios-backdoor