I really miss the individual bios and the nonsensical humour of the first two Sims games.
Also agree about Neighbourhood stories. I still feel as though the game is trying to force relationships and stories on me even though I've got it turned off.
Something I would definitely like to see in a Sims 5 game, and Sims 4, is less focus on mobile phones and no more phone calls from Sims asking for relationship advice!
I do feel that the Sims 4 has become a bit over-focused on relationships, to the point where a lot of the interactions have become mundane. It seems to me a little pointless to include the ability to have realistic conversation topics in a game where the characters speak gibberish, plus most of these interactions look the same.
Would be cool if the personality traits could have more effect on sims' mannerisms when interacting, like shy Sims in Sims 2.
This is just a personal preference, but I would really like to see, or have an option for more randomly generated occult townies with non-human/occult skin (green, blue, purple, etc). Would also love to be able to paint my Sims skin with different colours and patterns like the werewolves in Sims 4.
In general I would just like to see less obsession with mirroring real life (or at least, for this aspect to be optional for those of us who like to let our imaginations go crazy) and more of the nonsensical fun of the earlier games return in the next generation.