Monitoring Task Manager while playing shows that the game uses about 8-10GB of RAM when the game launches, and this steadily increases over 15-45 minutes to upwards of 25-30gb and eventually crashes with a DirectX error and popup about there being no more memory available.
Changing graphics settings doesn't seem to make a difference.
- GPU: 6950 XT 16GB
- CPU: Ryzen 7 5800X3D
- RAM: 32GB