I use an mchose l7 pro+ and a couple 8000mhz kb's. cidoo c60 silent and mchose ace 68 with ice rhinos for my arthritis hands. all cranked up lights full blast the mchose in berserk mode. One suggestion. I have my kb in one of the 3.2 10gbs slots that go to the cpu, next to the ethernet plug which is separate jack. THen I got one in one of the two 3.2 10gbs right next to each other, which also go to the cpu. The other 3.2 I have empty. all the usb 2 or I think 3.1 or 3.0 the blue, jacks go the mobo hub and I use them for everything else. the front case panel ones go to the chipset but I find it best to use the cpu ones. I have a 7800x3d with no performance hit. Can't speak for any systems below that but I can't imagine you would notice any decrease in performance. You definitely don't want to use the hub ones, and if the chipset ports are giving you trouble switch to the cpu ones. xhci enabled in bios.
