Re: No fix for Dead Space 3 crash on startup

This could be caused by a range of issues from video drivers to a corrupt Windows User Profile.

First, try running these setup files:

C:\Program Files (x86)\Origin Games\Dead Space 3\__Installer\directx\redist\DXSETUP.exe

C:\Program Files (x86)\Origin Games\Dead Space 3\__Installer\vc\vc2010sp1\redist\vcredist_x86.exe

Make sure you have all important Windows Updates installed, also .Net Framework and C++ Redistributables.
Be sure your video drivers and particularly your audio drivers are up-to-date.
Update motherboard firmware if you are using on-board sound.
Your Windows User account should have full admin privileges.
Run your GPU at stock speeds, not overclocked or factory overclocked.