Yes it is possible to play DA:O on a newer computer.
I had this issue in regards to Mass Effect 2 and 3 in recent playthroughs as well. Try this:
Start>Control Panel>Programs>Progams and Features>Nvidia Physx>Repair
Repairing the Physx engine will usually correct this specific issue. As for the issue the person who made the original post is having, most games (especially newer/not exceptionally old/some older games) require that you have -dedicated- graphics for their engines. Intel graphics will only get you so far, and I would never recommend that you use only the onboard GPU on a CPU for longer than you -have- to. You'll burn your CPU out extremely fast that way. If you're not using a laptop or a pre-built desktop that you can't open or modify I highly recommend that you purchase at least a GTX 400-700 series card. You need -something-