Game will not start

Windows Defender Anti-virus doesn't usually cause issues with DAI.  That has been mostly the realm of Avast, AVG and lately Malwarebytes. 

As far as the output adapters goes, you need to either use the onboard screen, or use a HDMI/display port for output to an outside monitor or TV.  You MUST use the standard video outputs instead of using an USB or USB-c cable so that the computer uses the proper display device.  So if you are just using your main laptop screen, then you should go into Nvidia control panel, and find the game, and make sure the settings are to ONLY use your Nvidia graphics card and to use maximum quality for the game.  Then you also need to double check all power settings so that the system doesn't default to Intel chip in an effort to "save energy" especially if you don't have the machine plugged in and are running off a battery.  You see, many default settings are to use the lower power using intel chip for graphics if running off a battery so that you can use the system longer.....but then this causes games to crash cause they aren't supposed to be using the intel chip in the first place.