Mass Effect 2 Invalid License Reason Code = Invalid Cipher (0x0006)

This is how I fixed that exact problem with my copies. I updated both versions until they both said they were ready to go. Meaning no more updates available. I did this in the Origin program by the way. I always launch my games with Origin instead of directly from the game. Anyway after I updated them both what worked for me was I update the regular version one more time and somehow it actually played the deluxe edition perfectly. But as soon as I try to update the deluxe one again it gets that license error. So update them both but update the version you won't be launching last. It doesn't make sense but that's how I fixed it on my computer. Also in my case Origin and Cloud saved all my data in a way that no matter which version I launched all my data including DLCs were available. Even when I uninstalled everything and redownlaoded it i still got all my saves back. So try updating them then launch the one you did not update last and it should work. That's how mine was fixed.