Mass effect 2 suddenly won't launch

Okay, I did the following:

Reinstalled EA app. (Origin won't even <install> now, so HAVE to use EA App.)

Reinstalled Mass Effect 2

Installed Visual C 2005. Tellingly, it never asked to repair, which indicates it was never installed in the first place.

Renamed the executables.

And after all that, ME2 FINALLY worked. However, I have a secondary problem. I had a stroke some years ago, and now need to use WeMod just to play the game at all. With the renamed executables WeMod won't run, so I have to use an unmodded ME2. Is there a way to get ME2 working without renaming files?

Or will I have to buy the Legendary edition? Hope not, Paying for the game twice blows.

Literally tried everything and nothing worked but I found another post here that helped me find the solution https://answers.ea.com/t5/Mass-Effect-2/Mass-effect-2-wont-launch-after-power-outage/m-p/9109402#M10823

It was a power outage issue so it was a corrupted save.

Hey, I have been trying for hours - I have

[1] Repaired

[2] Uninstalled the game

[3] Uninstalled Origin

[4] Deleted saves

[5] Disabled syncing to the cloud

[6] Enabled syncing to the cloud

[7] The suggestion to rename the files

Literally everything and my game will not launch, I have been playing fine for weeks and even this morning then nothing... please help!

Just for anyone in the future having a similar issue. I had a problem launching the game after applying a few mods. I disabled mods one by one then eventually reinstalled the game and was considering doing a fresh windows install. As a last resort, I realised I edited some nVidia setting via nVidia Inspector. Reverting these changed back to default and then applying one by one resolved my issue and I am fairly sure all it was was a mistype for one of the codes as it is completely fine now. 

The exact scenario I had in case you are troubleshooting. Once I launched the game I would get the Bioware intro and the first loading screen then once the menu kicked in I got Black Screen and heard music skipping through a sequence like very poor buffering. The game would crash about 10s Later. 

Hope this helps someone.

Thank you!!! Mine works!!!

@Kyle97Rubin 

• Go to your ">drive<:\Program Files (x86)\Origin Games\Mass Effect 2\__Installer\vc\vc2005\redist\" folder.
• Run the "vcredist_x86.exe" as Administrator. (Right click the exe > run as an Administrator)
  If you don't have an "Install" option, "Repair" the installation.
• Reboot.
• Test.

Hey there, my mass effect 2 game also does not get passed the "click any button to start" screen. I have done what you have asked, please let me know how to get my game to work. I have tried reinstalling, cloud saves off and repair and none of it works. Thank you.

doesnt work

Still the same issue..