Haven't progressed far into the game (playing from Europe), but I'm also experiencing this issue.
Each time the mouse cursor can be used (ie when reading a datapad or picking a reply on the conversation wheel during a cutscene), there's a chance that the mouse cursor doesn't disappear (as it should), but instead remains visible and centered on-screen.
One workaround I found was to open a menu (map, inventory, the esc. menu) and move the mouse. Reopening a datapad also seems to work. Upon exiting the menu the cursor disappears properly.
Not game breaking, but yeah, it does interfere with the immersion part.
My PC specs:
OS: Win 7 (x64)
Graph. Card: nvidia geforce gtx 760 (2GB)
Graph. driver version: 378.92
memory: 16GB
Mass Effect Andromeda version: deluxe edition, digital download
