For the first issue, I've found that letting VEE talk for about 3 seconds will bypass that "waiting for players".
The second issue is very annoying, given that you could possibly do a whole run of the challenge by the time the pop-up message disappears.
Third issue is crazy to me that it's even there. Why would you be unable to access the settings from anywhere in the game?
Last issue, I don't think that white text box has appeared in that position for me, so maybe it isn't a game issue?
Although the art style is very cartoonish, based on the trailer I have seen for a discord quest had shown that you can brake your wrist, destruction of cars was also in there by dropping a ramp on top of it, so hopefully we still get those brutal slams with bones breaking.