Okay, now I want CG to add Sister to the clones

I am against it because it is fan fiction. Just like I was and still am against Drogan. 

I am not against the idea of a transgender clone, but I don't think it's up to fanfic or CG to introduce such a concept, because they may or may not exist in the Star Wars universe. 

I would assume that clones are engineered to embrace only familial and selfless love and that they are likely pansexual if they have any sex drive at all or even genitals? We have seen no brothel activity or Spartan behavior.  It seems like something that would be "beneficial" and cost effective to simply remove if you want a tactical rather than an aggressive soldier/slave.

As asexuals or pansexuals, do they care about what physical bits are attached to them if any? That would likely be seen as an vanity issue rather than a gender issue. Obsessive vanity issues are likely a risk to the troops, and would be removed or corrected. So, I don't think they would make a big deal of it and announce and feel strongly about not being a part of a particular gender, that no one cares about, and that may get you in trouble. 

But what have we actually seen in the shows regarding clone gender? The clones do call each other brothers, but that may be a mistranslation from galactic basic to English - likely they mean sibling. They do have paintings of pretty girls (To Anakin's chagrin) on their drop ships, but perhaps they just didn't show us the ship that appreciates the beauty of Senator Bail Organa - so not necessarily gendered. For Cut and Suu, we don't know what kind of love that is with her and her children - there was a need and it was filled and loved. Seems pretty selfless to me. There does seem to be a preference for Twi'lek women, but that's universal, to their benefit and detriment, and not limited to species, gender or sexuality.  The gendered "clones" that we have seen, Omega, Emerie and Boba, are not part of the general clone population or their culture as a whole and are not good counter examples - They are technically clones, but were raised differently.

There are obviously anomalies, as we have seen, so we could see a transgender clone at some point, but the implications of their existence, or rather the recognition of their existence, would have repercussions on the clone "culture" as a whole and what is "normal". 

It is possible that "Sister" could become canon, but do we want to leave that up to a fanfic or CG? Perhaps a cisgender heterosexual clone would be the anomaly in an agender homosexual clone culture? We don't know. A kids show isn't going to show us that. Adding Sister may screw up that potential plot line. Or not. I don't know.

If it was just a normal biological humanoid culture that introduced a transgendered character and they had to struggle with their identity, that may be a valid story to tell. I get that you want to create representation in the art, I do, but I don't always support it. It just seems like forcing an Earth issue onto the Star Wars clone culture that doesn't reasonably care about that issue, and that writing has a tendency to pee off the fans. I also think in a world where you can have relations with actual aliens, most people probably wouldn't be so hung up on genders.

I may have missed or forgotten other clone aspects from the shows, and if I did feel, free to point it out.    

Perhaps an HBO show to explore this concept further? I'd probably watch. I liked the old show Alien Nation that explored alien sexuality and gender roles (they have 3!)

Ultimately, she is not canon and that is why I am against it. The rest are just my random thoughts.