For defense, you’re usually going to want to mod her for survivability. Her bonus protection is based off health, and you’ll want to also load her up with lots of tenacity to keep her from being dazed/stunned/etc. So whatever mod sets of health and tenacity you have, with health and tenacity primaries/secondaries when possible. Speed isn’t as important on defense, bc you honestly don’t want her taking a ton of turns and resetting her bonus protection all the time.
For offense, I find it’s more beneficial to load her with speed and potency so she can go often and land all her nice debuffs.
The strategy for her definitely varies from person to person, but this is what I have found to be very helpful. Also Zeta her if you haven’t already