Traya or ep lead both work pretty good.
Ep, thrawn, vader, +2 sith or empire will handle most padme teams and it requires even less investment than padme.
The strategy is pretty easy. Assuming you have decent mods on vader, he should easily go first. Force crush lands enough debuffs for him to go again. Merciless, then ability block everyone (especially padme). Then force crush again and saber throw jka.
Then fracture padme and keep the team stun locked and ability blocked to keep padme from healing them until you kill them.