Does placing new lots cause corruption?

I place new lots often and don't notice problems. I think the concern was more about breaking the world routing than like save corruption. A few years ago, I read a lot about it, too, and remember someone (maybe more than one someone) saying they'd only change a couple things in a game session, save and exit, then do more again later, which at least seemed to allow the game to rebuild the routing. So, that's the approach I've always taken. You could keep saves under different names along the way, so you can back up if something problematic pops up.