Re: Help! After changing some setting to Administrator, Sims 3 won't run :'(
@pinkdipi First, a couple of easy points. Yes, a third-party antivirus will override Windows Defender. That's by design and a good thing—having two antivirus programs running at the same time can and will cause problems. So Defender steps aside when another program is present.
The more resident sims your world has, the more RAM the save takes to run. Homeless sims (not residents) have only a small impact. To a lesser extent, the more objects are in the world, the more RAM is required as well. So yes, if you've been adding more households to the save, and existing sims haven't been dying off at the same rate, you've been pushing the save closer to the memory limit and therefore making Error 12 much more likely.
The "Run as administrator" option would be in one of two places: on a desktop shortcut or in the game's program files. Right-click the desktop shortcuts, if you have them, and select Properties > Compatibility, and you'll see a check box to run as admin. (The right-click Run as administrator option is only a one-time action.) The game's program files are wherever you chose to install them, and the .exe files are in the Bin folder. It would be in one of these locations by default:
C:\Program Files\EA Games\The Sims 3\Game\Bin
C:\Program Files (x86)\Origin Games\The Sims 3\Game\Bin
Check the executable files there and remove any run-as-admin settings you find. I would also suggest repairing the game afterwards; you can reapply the Lazy Dutchess patch afterwards.
If this doesn't help, please let me know which Lazy Duchess patch you're using, as there are several. Please also run a dxdiag and attach it to a post.
https://help.ea.com/en-us/help/pc/how-to-gather-dxdiag-information/