Last night I was able to get a solid hour of gameplay (not excluding the 7 saves I did 'just in case', each taking about 30 seconds). I think I might've almost found the solution to this.
1) Keep your graphics down as low as possible (it'll look horrible, but it's workable with advanced rendering).
2) Check to see if -all- of your Sims 3 Expansions are up to date. I found that my World Adventures, Ambitions and Late Night were all out-of-date with patching, so it's likely that if you've uninstalled, reinstalled and just patched after installing all of your EPs/SPs, something may be out of date. If any of the EPs I've mentioned have their second number as 0, it's likely out of date.
3) *EDITED TO ADD* I also found that I had a custom world installed. This was also uninstalled.
I haven't done -extensive- testing as of yet. I might re-introduce some of my graphics settings soon, but a solid hour of gameplay isn't too bad considering the all of 10 minutes I got initially, and the two minutes after uninstalling Sims 3 Seasons. This isn't a solution, but feel free to give it a try.
*SECOND EDIT* Okay, playing a second time and I had a crash within 20 minutes. Crashes no longer seem to stick to a certain time. The issue is exactly the same as the one had by Mac users, but I use a PC.
