@ariannaneal I actually waited a while before getting seasons (I got it about a month or month and a half ago?) because I was thinking it would just be a hassle to deal with weather, and I'm not that heavily hung up on 'reality' impeding too heavily in my Sims game 😉 . But... I really do love the seasons and have somewhat embraced the 'hassles' of dealing with weather. To me it's worth all of it just to watch the snow! I was amazed how beautiful it was when I was doing something in the game in the middle of their night in Brindleton Bay and panned out and snow was in the process of covering their 'world'. I just sat there and watched it and looked around a bit. It was simply gorgeous! I do enjoy the Seasons pack, though, and I think it's my fave for a number of reasons.
Anyway, if you don't have seasons, it should not be anything but the normal, vanilla weather in any of the worlds, as far as I know. Also, I think that the seasons pack - not the patch - is where the splicing for rare plants stops working - as we have mentioned here. I am having trouble remembering what changes I noticed with the patch. Can you remind me of specific changes you are noticing? As far as the Science Lab goes, I had mentioned that I was wondering if the buggy plants were tweaked in some way to help them not die (or maybe in some way that buffers them from the effects of Seasons features) both for those with or without Seasons that are playing that career. Even if it was a tweak, we think it's buggy anyway since employees are unable to harvest after one initial harvest, according to @PugLove888 's findings.
That would explain the lab plants, but on Sixam, as with any of the 'worlds's plants', you probably have to live/play in that world for several Sims days to several Sims weeks to have the plants mature (I believe this was also mentioned earlier in this thread). I haven't gone to Sixam yet, but that is the case when I want to harvest wild plants, or even a Sims' from their lot. I have to play, live at, and keep checking the plants in that location to get them to the point that I can harvest them. They will, however, get to the point where you can take a cutting from them sooner, and you can graft that onto another plant at home.