I have reached 100. As @phantasmkiss said pause a lot.
Also dont use high chairs - drag food to the floor near a toddler if their needs are red. Otherwise leave on counter they can reach it. If you have the movie pack get a popcorn maker ( thanks @MaggieMarley i learnt this from you.) Toddlers will eat from it autonomously.
You dont need to rush to change dirty baby nappies - they can cry for hours and wont get taken ( i play this challenge with the sound low so not tobe bothered by the crying) but keep them well fed or they are taken quickly. Lock the baby room for only the matriarch (and teen sims) or children wll block adults from getting to the babies. Or weird randoms who come in your home.
Also if you leave the lot make sure to bring your teens so the younger kids go to daycare and have their needs filled. Otherwise you come back and all toddlers and babies are at risk of being taken.