I own Vampires, but I rarely ever play any. When I play a save game, I just lock the bedroom doors for Household members only and if Vlad tries to break in, he just stands there for a bit and then leaves since he cannot even get into the bedrooms of my teens, young adults, adults, or elders to drink from them. Other Vampires that spawn just knock at my Sims doors after dark (which annoys me if it's every night) and I ignore them so they leave.
When Caleb and his sister are concerned, most I do with them is make my Sims learn the cure and have them get cured to normal Sims.
