I have very little lag in my game now. It looks like you can have a lot of sims in the game and it seems to run just fine but I need to use MC Command Center as you mentioned otherwise the game will start to cull them. It's also a good idea to use MC Command Center to clean up relationships.
It's also worth mentioning, one thing that helped my save was getting rid of a lot of custom content, turns out that adds a lot to your loading times.
Thanks for the information! That helps me not have to be paranoid about overpopulation for now.
I don't use many CC for CAS, and rarely use CC Build&Buy. If this will help avoid lagging, I will keep CC to be low amount and add only things I need.
