Get to Work is a fun pack with a lot of gameplay opportunities. I've cloned Eliza Pancakes, gotten vampire Lilith Vatore to Chief of Police, partied on Sixam, had males give birth to alien babies, and played alien families. Like an NPC Sim? Play them for a bit, and give them the same career as your Sim. Then, when your Sim goes to work, there they are (especially fun if you want to have an affair with a married Sim).
As with all the other packs, the only gameplay limits are your imagination.