@MoonlightGraham I think it depends on whether you like having each of your neighborhoods have a different flavor, where that flavor is defined by some sort of weirdness that you'd never experience in regular life.
Maybe you have a neighborhood where everyone is trying to be some kind of amazing artistic type, so they all are desperate for you to hear their music even if you're just trying to use a public bathroom in the park (Support the Performing Arts NAP)
Maybe you have a neighborhood where no one can put down their electronics and they want a little black future cube to tell them about the world instead of looking around them (Tech Support NAP)
Maybe you have a rough neighborhood where you might get beat up if you're not careful, even by your best friend (Roughhousing Encouraged)
And maybe in one neighborhood everyone makes cake for you.
If that seems fun, then go for it.
If not, then stay away from NAPs entirely.
(I believe you can still play Eco without NAPs, by turning off NPC voting.)