@CherryBerryCloud oof i forgot Salim Benali too, yes pretty sure he's meant to be arabic! (not sure of from where exactly , but meant to have arabic origins for sure). regarding some roomies, if it wasn't for their reference to "new girl" i'd have also guessed Zoe Patel is indian and Mitchell Kalani is hawaiian. regarding Liberty i also thought she was meant to be chinese but i wasn't sure.
as for Don Lothario, like you said the Lotario name is more known for a spanish character in The Impertinent Curious, a novel inside the Don Quixote novel by Miguel de Cervantes, but Don seems to be also inspired on Don Juan who is also a fictional spanish character. both Lotario and Don Juan main characteristics are their seducer and libertine nature, so i guess devs took these references and made him.