Only trait I avoid like the plague is the Kleptomaniac trait because I do NOT like it when Sims come into my Sims' home and take things. None of my Sims have it and I faithfully remove it when I encounter it with townies/NPCS/unplayed premades.
All other traits are fair game and I use all and rarely change change them even those that are not my favorites like Unflirty and Jealous. I have changed out traits but mostly because I want Sims to have traits I find might suit them better or when traits conflict-like cleaning and squeemish. Those two do NOT mesh well in one Sim. I have a teen that has those two and I have to swap either one out next time I play her household.