Gshade toggles not working

I've had gshade for a long time now and today i decided to get relight and try some new presets out. Everytime i load into my game and toggle ADOF for example it does nothing, when before it did. I tested it on my old presets that it always worked on but still, nothing. Its the same for MXAO and a few other toggles. I cant edit the amount of them or turn them despite the box being ticked. I've uninstalled and re-installed a few times now and each time its the same. Not sure what caused it or how to fix it.