If you are not mixing CC in with this, then my answer is with a good number of mods.
The main mod I will not play even load up my game if it is broken is the MC Command Center mod. It just does way to much to play without. The story progression alone can lead to some pretty comical events and coupling. I have to say that, by far, the best moment in my game was when MCCC had Don impregnate Bella twice, then turn around and have him marry Cassandra.
Mods that limit typing in cheat codes, enhance or add to game play. I had blast when Shinya was Super Star Serial killer going around and killing obsessed fans.
Lastly, if it fixes a glitch, I have it in my game.