This issue now seems to be fixed in the 1.68.154.1220 November 2020 patch.
Thanks all for confirming it now seems to be fixed. If you start experiencing issues again please post 🙂
Disabling Origin had no effect.
Given that the issue seems to be triggered by rotating the camera, I tried playing with the Sims 3 camera. I had very occasional rainbow wheels and framerate drops (on a fairly simple lot) when zooming and changing stories, but overall I was able to play normally for 46 minutes.
Around the 30 minute mark I switched to the TS4 camera, and 15 minutes later while dragging to resize a room, the cascade of freezes began and I had to save the lot and quit the game one painfully slow click at a time.
I don't know if the TS3 camera was significant, but anecdotally I was able to play for a lot longer than before until needing to shut it down.
As an additional datapoint;
My MacBook Pro had to go for rather extensive repairs, where they replaced the logic board and the GPU, and totally wiped the hard drive.
After re-installing The Sims 4 on the now-fresh machine, the same glitch started happening maybe 30 seconds into loading a lot, again triggered by dragging the mouse to rotate the TS4 camera.
Didn't bother to try with the TS3 camera again, as it's been a long day of restoring backups and re-installing everything...
