Not enough space

@hatchedcleric41  How much free storage do you have?  If you have more than one drive, please let me know the free storage on each one, as well as the drive(s) on which Origin and Sims 4 are installed.  If you're not sure how much free storage you have, you can run a dxdiag instead.

https://help.ea.com/en-us/help/pc/how-to-gather-dxdiag-information/

Please also let me know which version of Origin you're running.

I have 361GB left of my C drive and 18.3 of my D drive. Origin is installed on my flash drive but sims 4 is installed on my c drive.

@hatchedcleric41  Is your flash drive your D drive?  It doesn't actually matter; what does is how much space is left on the drive where Origin's download cache lands.  Even though your C drive has plenty of space, if Origin is trying to download somewhere else, it can throw that error.

In any event, the first thing to try is clearing Origin's cache:

https://help.ea.com/en-us/help/faq/clear-cache-to-fix-problems-with-your-games/

If that doesn't help, you may need to temporarily install Origin on C, at least long enough to get past this error.  Then you can move it back again.  Clear its cache a second time, then uninstall Origin (just Origin, not your games) "the hard way," and reinstall.

https://help.ea.com/en-us/help/origin/origin/manually-uninstalling-origin/