@crinrict I do use both custom content and mods in my game but I believe they were either deleted or disabled when I uninstalled the game to reinstall it. Also, the game crashes when I open it and it gets to the"The Sims 4" screen. It has been a while since I've seen a plumbob.
Try updating your drivers then and if that doesn't help, try resetting your user files as described in the factory reset described in this post: http://answers.ea.com/t5/The-Sims-4/FAQ-Troubleshooting-Steps-amp-Known-Issues/m-p/3621199
The folder should not have been deleted when you reinstalled (although I'm unsure if there's a question these days if you want to keep your user data or not).
You won't loose anything. Just make sure to not delete any files and make a backup.
After renaming, repair your game by right clicking on the game in Origin.
Try on a new game with nothing added back first (start new game). If it works, put back your save game and try again. If it still works, you can start putting stuff back.
The rest does not need putting back, cause they are mostly cache files that recreate or log files that are not needed for the game.
I'm really bad with AMD stuff but isn't there some non-beta driver that's newer then 2011 for your card ?
I'll see if anyone else can help you better with this.
