@199120221311  Please get rid of Sophos.  The point of asking about an antivirus was never to suggest that this person add one; it was to address potential issues arising from one already installed.  Adding Sophos to the mix can only complicate things.
Please run a couple of basic checks on your Windows system files:
- Hit Windows key-X
- Choose either “PowerShell (Administrator)” or “Windows Terminal (Administrator),” whichever option is offered
- Inside the window that appears, copy and paste “DISM.exe /Online /Cleanup-image /Restorehealth” without quotes into the window, and enter
- The system will start validating soon. If it throws an error, please list it here
- After it reaches 100%, hit Windows key-X again
- Again, choose “PowerShell (Administrator)” or “Windows Terminal (Administrator)”
- Inside the window, copy and paste “sfc /scannow” without quotes into the window, and enter
- Post the message you receive here
Restart your computer, hit Windows key-i, select Update & Security, and click the box to check for updates.  If any install, restart again afterwards.
Then move your entire Sims 4 folder out of Documents\Electronic Arts and onto the desktop.  When you launch the game, if it opens at all, a clean folder will spawn with no content.  Don't add anything to it yet; just see whether you can get far enough to start a new save and play in live mode for a bit.  If so, you can start adding your saves and other content from the old Sims 4 folder to the new one.  Keep testing so you find out right away if the game stops working again.
If you can't play even after moving the folder and before adding anything to the new one, please look for new errors in the Reliability Monitor.  Hit Windows key-R and enter "perfmon /rel" without quotes, and you'll see a chart of errors and updates with a column for each day.
For any errors that mention Sims 4 or Origin, or any that happen at the exact time you try to launch the game, right-click on the error name and select "View technical details," then copy the info and paste it here.  I'm only interested in errors that happen after you move the folder.  If you don't see any, let me know; that's useful information too.