Game Won't Load- Menu Screen Grayed Out

Every time I get an event pop up, when I close it out, the screen is grayed out and frozen, it's unusable.  I then have to pull up task manager to end the task and try to restart.  I have removed mods, cleared cache, repaired the game. Nothing works.  This happened last week during event pop up but eventually I got in so I assumed it was a one time glitch.  However, I have tried 5x today and I have still not been able to get into my game. 

many tries to bring it back up for that one.