Unable to Start Error on Mac

I keep getting the ....

"Unable to start:

Cannot start because game data is missing or damaged. If you have Mods installed please remove them and try again.  If not, please repair or reinstall the game via Origin.

[de4ee14f:29f00e76:00000000:4b0d852b]"

I  removed all mods and repaired the game.
Open Sims, works fine. 
I install the mods back.
I open the game, play it with mods, it runs fine again, (it ran for 3 hours, playing with the same exact mods) 
I hit save, come back the following day and I get this error message.

I have repaired the game. 

I have also removed the entire game, downloaded it back. 

It was working fine last night. I have all my mods downloaded through the TSR CC mod manager.  This same thing has happened  3-4 days this week. 

I am becoming unbelievably annoyed with this. What could cause this? 
I am on MacBook Pro.


I also should add, I have moved the entire Sims 4 folder out of Documents > Electronic Arts and onto my desktop .. it just creates a new sims4 folder in documents.