It hit my two lower level cities over the weekend.
My level 21 city (which is really just a feeder that looks very nice) was easy to fix.
My level 51 city was not easy to fix - even with the gifted service buildings, it still was not enough to overcome the demand in my regions, so I got frustrated and just demolished every single residence in all four regions. I have zero intention of building in the regions again.
Epic buildings are major consumers of service capacity - the game pushes you to upgrade regular residential zones to Epic buildings, so naturally my level 51 city had a decent amount spead amonst the regions. Now the epic buildings like quadruple demand. Epic buildings are not worth any effort - If you have a ton of them, consider demolishing some. I won't be do anymore epic projects.