TVF is almost right.
Technically the best guess we had for the original rate was 1-in-3 per sim. Since the kept the rate the same for 6-energy nodes, the new rate would be 1/3 divided by 6, or 1-in-18 per point of energy spent. Since the game doesn't allow you to get 2 tickets for a single sim no matter how high your chances, any node that requires more than 18 energy per sim is going to sacrifice a small part of your chance-per-energy, since anything over 100% is the same as 100%.
There are no nodes over 18 energy per sim except 20-energy hard nodes, so if you aren't simming those, it doesn't matter which node you sim, not even a little bit. If you are swimming 20-energy nodes, it matters a little bit, but not much. (You are sacrificing 2 energy out of every 20, and can expect your quest to take 11% more energy to complete as a result.)
This is, of course, assuming the crowd-sourced average of 1-in-3 is correct (which would carry with it that the drop rate per point of energy is 5.555% instead of a flat 5%). There's little chance it was more than that, but if it was less, then the loss you face for a 20 energy node is even smaller. At 5% (TVF's very good estimate, but still one that has some error margin) or lower, even 20 energy nodes cost exactly the same amount of energy for unlock (on average).
So... I personally wouldn't worry about it, but if you're looking to truly maximize efficiency, you could avoid 20-energy nodes.