@smdHannah Right, I meant are you able to change any of the other options, aside from fullscreen/windowed, without the game going haywire. But if the answer is no, the next step is whether you use OneDrive, and if so, whether it's syncing the contents of Documents. If it is, it might be interfering with any changes you try to make to options.ini. The easy test is to pause syncing for a while. You may also need to cancel the current sync.
https://support.microsoft.com/en-au/office/how-to-cancel-or-stop-sync-in-onedrive-4885c27e-3d89-4d69-be75-2646c71367d3
If that doesn't help, or you don't use OneDrive, try playing in a clean boot:
https://support.microsoft.com/en-us/topic/how-to-perform-a-clean-boot-in-windows-da2f9573-6eec-00ad-2f8a-a97a1807f3dd
When you reboot, go through the Task Manager's background processes list shutting down anything that doesn't absolutely need to be running, for example RGB software or MSI Afterburner. If you accidentally kill the wrong process and it doesn't restart itself automatically, just reboot your computer. Please also disable your antivirus and any other security software, at least long enough to test. As long as you don't do anything other than try to play, your computer should be safe.
While you're doing the above, please also use a clean Sims 3 folder, as in, move the existing one out of Documents\Electronic Arts and onto your desktop and let the game spawn a new one. This will include a(nother) new options.ini, so all your changes will have reverted. As always, please either edit the file manually, or change graphics settings at the Main Menu and then quit to desktop before loading a save.