Other than the obvious, making sure something is not infected with a virus, then I would say yes.
The way Sims4 is designed, if a mod causes problems, all you have to do is delete it if it's the culprit. I am quite impressed at how the dev team for Sims4 made mods a separate add-on rather than having a program that changes the base-code itself.
For example, I have a mod that makes eating and drinking a bit faster in-game. It doesn't change the base-code, just with the mod overrides it while the mod is in the mod folder. If anything messed up, all I have to do is remove it.
As for CC, if it stops working for whatever reason, then it can be deleted. Like if it's missing a mesh for the texture of a shirt, then it won't ruin anything in the game, just have something weird on-screen for that particular shirt until it's disabled or deleted. ;)