I have one save that I foolishly put a bunch of my sims in, so now I'm in the process of culling (man I hate that word) some of the ones who can be just utility sims. The favorites are mostly in here, I have a whole nest of vamps who are going to be making generation number 3, a hallmark for me, lol. I have normal sims who are intertwined with the vamps who I am very attached to, jungle explorers who I love (husband & wife team) and who have taught their daughters about archeology. I have other saves that are just single sims, one to each save. I found if I had multiple saves I would only be able to spend holidays with each one in rotation. Some don't get Christmas but once every 5 years, which is sad for simmies with kids.