Jacques Villareal's Wife...

Theories i've thought of. Idk if others have thought them up too
Mrs. Villareal may have run away from home for Jacques' abuse or for blaming herself for Max turning out evil. In transit to her destination, she stayed in San Myshuno at 1313 21 Chic Street where she was murdered by Penny Pizzazz, Olive Specter or one of the Fengs (This would explain who the corpse in 1313 21 Chic Street is and what happened to Mrs. Villareal

Speaking of the Fengs, Mrs. Villareal was an investigative reporter trying to take down the Feng Corporation so they sent the Mafia to take care of her. The Mafia told Jacques to deal with her or his children would be taken so he did. Trying to investigate the Mafia himself for revenge, Jacques went insane.

She was bitten by Vladislaus Straud and became a vampire and so she ran away from home to try and protect her family from herself. Finding great pain in being away from her family for their sake, she gave herself the nickname, Miss H*ll (Marybell Smith).

Mrs. Villareal was born the fairy, Titania Summerdream traveled from Innisgreen, Veronaville or Moonlight Falls to find a love in Windenburg. She met Jacques and had a good relationship with him until she was spirited away by fairies who were disgusted that she chose to be with a human. The Fairy elders had a witch cast a spell of forgetfulness on her and she lost all memory of her family in Windenburg and they arranged for her to be with Oberon, with whom she had Mara Summerdream