I've been playing this game for roughly a year and a half, and already made myself guilty of all the seven deadly sins.
Pride: I confess to punishing my sims harshly for disobeying me, their God, like keeping sims who didn't go pee when I told them to away from the toilet until they wet themselves.
Greed: I confess to throwing innocent premades out of their homes whenever I need their lots, and since I don't play them anyway, I don't even bother moving them somewhere else.
Wrath: I confess to once killing a child patient for ruining my doctor's promotion by displaying all the wrong symptoms and causing the doctor to make a wrong diagnosis.
Sloth: I confess to letting a sick cat suffer for days because I was too lazy to take her to the vet again, feeling she should finally learn her lesson about constantly picking fights with squirrels. Of course, she didn't.
Lust: I confess to having a brothel in San Myshuno.
Envy: I confess to overthrowing leaders of premade clubs because I wanted them for my own sims.
Gluttony: I confess to making a sim version of an abhorrent workmate and making her the maid and primary food source of a very hungry vampire family.
And my biggest confession is that I don't feel sorry for any of this.