I play several households on rotation, some more often than others.
Lifespan is on normal and I use full autonomy. At the moment I am mostly rotating between my 18 San Myshuno households and around 10 on other worlds. All of this Sims are connected in some way, so I want them to age in a realistic way - if kids hit the adult stage I switch to their parents to make sure they will be almost elder or even turn to elder. I take care of siblings, so their families will age up around the same time, so cousins will be around the same age and so on.
It's a lot of work and I only reached generation 5 in 1.3k played hours, but I like it that way.
For the next weeks I will play a bit more relaxed, because nobody should age up, as I have specific plans for all of them when "get famous" will be released.