Which business would you want?

I'd also like our sims to be able to make things to sell in their shops and I would really like to make toys and have my sims run a toy shop selling the things they make there.

None. There are plenty of games that simulate businesses, and they generally do a better job at it because it's the only point of the game. Every time they create some sort of business for Sims to run, all I hear about is the bugs. Sims are too multi-faceted to behave properly in a business simulation, and people get frustrated because the NPCs (or their own Sims) aren't doing what they're supposed to do.

Then again, the work aspect is probably my least favourite part of the Sims - my Sims usually don't have proper jobs. Work is the last thing I want to think about when I sit down to relax and play with my Sims.

Definitely hotels. But I would also love a tattoo/piercing parlor.

Before the style influencer career came along, I was hoping for a salon type of business to come at some point, I really like the idea of sims coming in with a specific budget and look in mind and it’s up to the player to fulfil their wishes, and based on the service the customer received the player would get a set amount of tips or something similar. But now that we have the style influencer career I’m not sure if that will ever be a thing.

I really want hotels and also live-in Bed and Breakfasts. The ability to run campsites with OR would be good too. Resorts or "Dude Ranches" would also be great and give me something to do with massive lots.

Hair Salon would be soo awesome! I loved it in TS2 <3
Daycare was also one of my favorites in TS3 (although I'd actually prefer a venue over an in-home establishment).

But as for one we've never really had officially, I'd really like the idea of a jeweler. Similar to how florist really piqued my interest in gardening. A jeweler would really give me a reason to collect special rocks and materials. Also the thought of crafting special engagement rings would be pretty awesome too <3.

Hotels if I had to pick just one of the options. Ideally, though, I'd want all.

I would also like to see the return of the pay-per-hour metre from Sims 2 Open For Business. With that bad boy, you could turn anything into a business (I run several cemeteries using it) and I would like more options along those lines rather than set perimeters and restrictions.

Yes, we need to have hotels and B+B's. I wish we could even rent out apartments. Maybe one day. We need a place for our homeless sims to make gameplay more realistic.
Or even a pack with a feature that allows you to have more than one venue on a lot?

A Morgue. I think being a mortician would be really fun and interesting.

I'd love to have hotels B)!