Thanks for all input! I was expecting (or hoping for, even) a more clear answer like the majority noticing a change with a certain pack added. But of course, our rigs are different, and the combination of different packs might also play a role, I guess.
Yes, cc and mods do affect these things, but I wanted to know if a few packs were heavier than others, in the sense of perhaps avoiding the very heaviest one, if I don't already have it on board, that is :)
For lag in general, I score quite badly on all accounts: 6 trillion cc items, 7 years old save with 100+ actively played houses, and tons of history and relations that the game needs to keep track on. At times I feel sorry for my game, LOL. I'm aware that old saves might cause lag (I get rid of most, but keep some for time saving re specific video productions etc. Also the library (in my case mostly households) and screenshots folder might impact. Inventories I'm aware of, but not very good at keeping clean, so I added a new tradition "Attic Cleaning Day" which was meant for cleaning all inventories, but it's practically impossible to stop by 100+ households during that one simday, LOL. It's still acting as an annual reminder in my calendar, though...
Re CoL taking more tech recourses, I think it helps turning off the sparkling hood effect from ECO Lifestyle, as farming often trigger this positive environment, at least in my game it seems to do that, and especially in H-on-B.