I usually play one family through generations (legacy style I guess, without rules though) and ignore premades because their names are themed/gimmicky and get on my nerves, but this time I decided to try rotational play to mimic some type of story progression. The Lewis/Kim genes line has produced some lovely looking sims, and surprisingly so has Cassandra Goth (though her surname is now James). Poor Alexander Goth grew up unfortunate-looking and looked perpetually sad, so I took him into fulleditmode and transitioned him into Alexia, and she made a wonderful wife and mother ;)
Don Lothario has excellent genes, but beware; despite his noncommital trait he's oddly clingy, and despite being dead for quite awhile, still calls up his great grandchildren to invite them out for dinner :D
