Have all of you with lot-loading issues removed all of your cc, too? I recommend taking EVERYTHING out, if you're having issues getting the patched game to work properly.
Any script mod stands a VERY good chance at being broken, if it has a pre-patch filedate. UI mods, too. Update any mod or cc item you want to keep playing with, if one is available. At least check to see if it's been verified as working post-patch.
And CC. I haven't seen a LOT of broken cc reports, but, I don't go a lot of places where I would, either. I have seen some. So there are problems at least POSSIBLE.
CC is *usually* safer. But it melted when Dine Out came out, too. And other times. Check everything. Game's touchy, and an EP is a MAJOR update.
Some things will be fine. But is not checking from scratch (vanilla game and add verified files back SLOWLY) *really* more important to any player than possibly losing (or, better plan, KEEPING) a 9th generation hood?
(I don't mean that to sound snarky. I've just been fielding a lot of "OMG my game won't work" questions since the patch, a few repeatedly, and I'm a little frazzled.)
Time is not on my side, today.