[CURRENT ISSUE] Anti-Virus blocking User Folder (Screenshots/Gallery/Mods..)

my mods don´t work after update. I enter the game, I clicked on game options and I enabled the options for the mods to work, I saved the changes and I left the game. Although, when i go back the game, the options for the mods to work aren´t enabled, as if i never had activate them. Help please! (english is not my first language, then please, don´t use abreviations, please)