(FINAL MISSION SPOILERS) Veilguard restarted my PC during the final mission.
I was pretty far into the final mission. Lucanis struck down Ghilan'nain, Solas betrayed me and had me replace him in the Fade Prison. Just as that cutscene ended and I was supposed to be back in gameplay, the game suddenly went from full-screen to some sort of windowed mode. Then it froze, my computer made a strange noise I can't recall ever hearing before and it restarted.
I was playing the game via Steam. It had been a lengthy session. Slightly broken up by me changing a single graphic setting and having to restart .
I was testing the "High" setting on Texture Quality. I found it not worth the reduced frame rate and turned it back to "Medium", thus restarting my PC again before continuing to play until my PC suddenly restarted, seemingly by itself, because of the game or some other reason I don't know.
Added spoiler tags: Holger1405.