Game causes my PC to crash

I can play for some time (30 minutes up to 2 hours) then the game crashes. It starts with the game not responding to inputs (like, I'll press the hotkey for the journal, but it does not open). Then the game freezes while I still have sound. I can close the game with alt+f4 but then my PC is not responding or rather all of my inputs are delayed (if I press the windows key it takes up to 2 minutes until the start menu is finally open). At this point, I need to restart my PC.

I play on an AMD RX 7900 XTX with the newest driver (24.20.1905). Lowering the graphic settings in game does not help as well as limiting the FPS to 60 or 30. I can play the game just fine with constant FPS until it crashes.

Other games like Cyberpunk or Starfield are running fine with the highest graphic settings and no crashes.

CPU: AMD Ryzen 9 7950X3D
Board: ASUS TUF Gaming X670E-Plus